CANARY Biological Threat Detection

CANARY Biological Detection Technology

CANARY® is a tested and proven method of pathogen threat detection, providing users with an unprecedented level of speed and sensitivity in both commercial and defense applications. Originally developed by MIT, CANARY technology allows the detection of a wide range of pathogens including bacteria, viruses and toxins.

How It Works

Canary uses a genetically engineered immune cell called a “Biosensor” to:

  1. IDENTIFY & BIND to a specific target
  2. LUMINESCE when the target is found

By measuring light output from the cell, we can tell if the target biological is present in the sample.

Current Biological Detection Methods and Their Limitations for Field-Use

CULTURE

Considered the “Gold Standard,” this method puts a sample in a petri dish and waits for the pathogen to grow. It is extremely sensitive but requires several days to get results.

PCR

One of the most commonly used methods, PCR looks at the DNA of a sample to tell if a pathogen is present. It is quite sensitive, but requires hours and technical expertise to extract the DNA for testing.

Lateral Flow

While this method is rapid & inexpensive it has performance issues and sacrifices sensitivity. In environments where exposure is a health and safety risk, this method fails to provide reliability.

CANARY breaks though the limitations of current biological detection methods for field- use. It combines the sensitivity of PCR with the speed of Lateral Flow, allowing users to accurately test for tiny amounts of pathogen in minutes. The method requires very few materials, time, and minimal scientific expertise.

SPEED

If a pathogen is present, it only takes seconds for the Biosensor to bind and luminesce, giving you results in under 5 minutes.

SENSITIVITY

Imagine the biosensor as a cell covered in light bulbs with a switch. With other technologies, when a single pathogen is present the switch turns on one light bulb. With CANARY, the switch turns on all the light bulbs. This amplification of signal makes CANARY incredibly sensitive.

EASE OF USE

No complicated extractions. No waiting for bacteria to grow on a plate. No long lists of required buffers and materials. Minimal scientific expertise needed. Once your sample is prepared, tests can be run in 3-5 minutes. Our software algorithm automatically interprets the data for you, giving you the timely results you need.

UVC light disinfectant processes to combat COVID 19

UVGI - Ultraviolet Germicidal Irradiation

UVGI requires a UV (ultra violet) mercury bulb with a minimum radiant energy output of 254 nm of light. This disinfection process is applied to surfaces as well as supplemental air cleaning used in reducing the transmission of airborne bacteria and viruses. UVGI is used in air handling units and ductwork to limit or prevent vegetative bacteria and fungi and viruses and also in “scrubbing” the conditioned air flow to remove airborne contamination. Other applications are upper air room disinfection units and HEPA filtered air purification devices. Up to a 90% reduction of targeted contaminants has been documented.

UVC PHI - (Photohydroionization)

This extended air purification process within the ductwork is enhanced by using a quad metallic compound target around the UV-C bulb which provides an advance oxidation process producing hydro-peroxides, super oxide ions, ozonide ions and hydroperoxides called the Advanced Oxidation System (AOP) into the air stream which reduces airborne microorganisms up to 99.9%. Gases, VOC’s (volatile organic compounds) and odors are also reduced significantly. Up to a 99% reduction of microorganisms has been documented. The output level pf hydroperoxides is between .01 to .03 PPM below the Government safety guidelines of 1.0 ppm.

UVC-PCO (Photo Catalytic Oxidation)

A similar level of AOP is accomplished by the use of a metal oxide semiconductor, usually titanium dioxide or cobalt oxide around the UV-C bulb.  This technology has been created by RGF and Sanuvox. RGF has produced a REME HALO unit that is easily inserted into the forced air ductwork. It oxidizes through the use of Oxygen also. Similar results of germicidal and viral reduction up to 99.0 % have been reported.

UV-C CUVC (Crystalline- UVC) Air Disinfection Device

This patented technology is unique to Aerobiotix, the country’s leader in reducing SSI (surgical site infection) in an OR setting. The design of this system is to maximize UVC dosage and inactivation efficiency while maintaining high air flow volumes. The C-UVC device utilizes a hybrid of biological and physical systems utilizing a reaction chamber filled with clear cylindrical crystals. These crystals function as a solid media filter, slowing and trapping organisms as they pass via the air stream. The unique feature is that these crystals can be penetrated by UV-C irradiation and inactivated occurs within one air pass. This has had the effect of increasing the inactivation efficiency over prior UV technologies.  The addition of HEPA air filtration and PCO using zirconium oxide as a catalyst, eliminates VOC’s, elevated RPC ( respirable particle counts)  and odors as well. This has resulted in the continual production and maintenance of the highest level of air quality to date, validated to eliminate > 99.9% of viruses, spores and bacteria.  Different units are designed to disinfect targeted indoor air spaces as well as HVAC systems.

Aerobiotix UV-C CUVC Air Disinfection Device