Get Validated Results in as Little as 15 Minutes
BioFlash Biological Identifier
Initial testing has proven that the BioFlash® Biological Identifier detects airborne SARS-CoV-2 in a laboratory setting, after evaluation and verification by the United States Army Medical Research Institute of Infectious Diseases (USAMRIID). BioFlash uses Canary® detection technology, a cell-based biosensor that accurately detects and identifies biological-threat agents including viruses, toxins, and bacteria.
These same validated results are available in the field in a real life setting using this innovative and proven CANARY technology. Testing may be done in as little as 15 minutes or up to 8 hours. Results are reported within a few minutes after completion of the testing!
USAMRIID Verification & Results
Table A: USAMRIID Evaluation of BioFlash to Detect Aerosol SARS-CoV-2
|Target PFU*||Number of Aerosol Tests||Number of Positive Results||% Positive|
Table A shows the accuracy of detection and identification by the BioFlash of SARS-CoV-2 in in the air at different concentrations.
In 6 out of 6 aerosol tests, the BioFlash detected down to an estimated 6000 infectious particles of COVID-19.
The estimates in table B provide a comparison with particles emitted in normal activities by a person infected with COVID-19.
Table B: Estimated Virions Released Per Human Activity Type
|Human Activity||Estimated Infectious Particles Released|
|Sneeze||up to 1,000,000 per sneeze|
|Cough||up to 100,000 per cough|
|Talking||up to 10,000 per minute
(300,000 per 30 minutes)
|Breathing||up to 1,000 per minute
(30,000 per 30 minutes)
BioFlash COVID-19 Use Case
Using breakthrough CANARY Technology, BioFlash overcomes the limitations of current laboratory-based biological testing methods, allowing pathogen identification to be conducted on-site or at the place of operation.
Canary combines the sensitivity of PCR with the speed of Lateral Flow, allowing users to accurately test for tiny amounts of pathogens within minutes. The method requires minimal materials and time, and no scientific expertise.
The BioFlash can be used where there is a high risk for transmission in indoor environments:
As new threat pathogens emerge, such as superbugs and biological warfare agents, BioFlash’s detection capability will continue to evolve.
Currently available biosensors detect anthrax, smallpox, listeria, biological toxins such as ricin, as well as other high-interest threats.
How Canary Technology Works:
CANARY Biological Detection Technology
CANARY® is a tested and proven method of pathogen threat detection, providing users with an unprecedented level of speed and sensitivity in both commercial and defense applications. Originally developed by MIT, CANARY technology allows the detection of a wide range of pathogens including bacteria, viruses and toxins.
How It Works
Canary uses a genetically engineered immune cell called a “Biosensor” to:
- IDENTIFY & BIND to a specific target
- LUMINESCE when the target is found
By using light output from the cell, we can tell if the target biological is present in the sample.
Current Biological Detection Methods and Their Limitations for Field-Use
Considered the “Gold Standard,” this method puts a sample in a petri dish and waits for the pathogen to grow. It is extremely sensitive but requires several days to get results.
One of the most commonly used methods, PCR looks at the DNA of a sample to tell if a pathogen is present. It is quite sensitive, but requires hours and technical expertise to extract the DNA for testing.
While this method is rapid & inexpensive it has performance issues and sacrifices sensitivity. In environments where exposure is a health and safety risk, this method fails to provide reliability.
CANARY breaks though the limitations of current biological detection methods for field- use. It combines the sensitivity of PCR with the speed of Lateral Flow, allowing users to accurately test for tiny amounts of pathogen in minutes. The method requires very few materials, time, and minimal scientific expertise.
If a pathogen is present, it only takes seconds for the Biosensor to bind and luminesce, giving you results in under 5 minutes.
Imagine the biosensor as a cell covered in light bulbs with a switch. With other technologies, when a single pathogen is present the switch turns on one light bulb. With CANARY, the switch turns on all the light bulbs. This amplification of signal makes CANARY incredibly sensitive.
EASE OF USE
No complicated extractions. No waiting for bacteria to grow on a plate. No long lists of required buffers and materials. Minimal scientific expertise needed. Once your sample is prepared, tests can be run in 3-5 minutes. Our software algorithm automatically interprets the data for you, giving you the timely results you need.